Expedia inc. uses various distribution methods that can be considered b2b and they do this using different brands.
Expedia sell through affiliate programs where a site joins the program and refers users via a traceable link to the Expedia website. The commission is then split between the referrer and the affiliate program company.
EAN (Expedia Affiliate Network) is a separate company in the Expedia Inc. group focused on b2b only. It offers a Chameleon site that is free of cost and a travel affiliate can integrate this into their site by adding a widget. EAN also offers an XML API solution. A seasoned developer could help integrate this into a travel site and give a good user experience to their visitors. The commission starts at 5% that is paid once the accrued commission reaches $50. An important thing to note here is that the commission is only paid on the net rate that is after deducting the tax from the total amount. Once the performance increases, this commission keeps increasing. We have seen affiliates make up to 12.5% gross commission.